Short Description
Etofylline and Theophylline 450 mg is a combination bronchodilator used to help manage airway obstruction associated with respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It contains etofylline and theophylline, which help relax the muscles of the airways and improve airflow.
What Is Etofylline and Theophylline 450 mg?
Etofylline and Theophylline 450 mg contains two related bronchodilators: etofylline and theophylline. Indian regulatory records list a 450 mg tablet strength containing etofylline 346 mg and theophylline 104 mg.
The combination belongs to the methylxanthine group of bronchodilators and is used to help reduce reversible airway obstruction in certain respiratory conditions.
Uses
Etofylline and Theophylline 450 mg may be prescribed to:
The appropriate treatment and dose should be determined by a healthcare professional based on the condition being treated and the specific product formulation.
How Does Etofylline and Theophylline Work?
Etofylline and theophylline are bronchodilators that help relax the muscles surrounding the airways. This can widen the air passages and improve airflow, making breathing easier.
Theophylline also has effects on several cellular pathways involved in airway smooth-muscle activity and inflammation. The clinical response varies according to the condition and individual patient.
How to Take Etofylline and Theophylline
Take Etofylline and Theophylline exactly as prescribed by your healthcare professional.
Follow the prescribed dose and schedule carefully.
Take the medicine consistently in relation to food, as changes in how it is taken with meals may affect theophylline absorption.
Take the tablet as directed for the specific product supplied to you.
Do not change the dose or stop treatment without medical advice.
If you miss a dose, follow the instructions supplied with your medicine or ask your doctor or pharmacist for advice.
Theophylline has a relatively narrow safety margin, and changes in dose or factors affecting its metabolism can increase the risk of toxicity.
Important Safety Information
Tell your doctor or pharmacist about your medical history and all medicines, supplements, and herbal products you use before taking etofylline and theophylline.
Use particular caution if you have:
A history of seizures
An irregular heart rhythm or other significant heart disease
Peptic ulcer disease
Liver disease or other conditions that may affect theophylline clearance
Heart failure or other serious illness that may alter theophylline levels
Changes in smoking habits, as stopping smoking can affect theophylline clearance
Important interaction categories include medicines that increase or decrease theophylline metabolism, including some antibiotics, medicines for seizures, and other medicines that affect liver enzymes. Changes in smoking status can also alter theophylline exposure.
Check possible interactions with your doctor or pharmacist before starting or changing any medicine.
Pregnancy & Breastfeeding
If you are pregnant, planning pregnancy, or breastfeeding, speak with your doctor before using etofylline and theophylline. Theophylline can cross the placenta, and pregnancy can affect the way the medicine is processed in the body; treatment should therefore be assessed by a healthcare professional.
Theophylline passes into breast milk. If you are breastfeeding, your doctor will consider the potential benefits of treatment and possible effects on the breastfed infant before recommending continued use.
Side Effects
Like all medicines, Etofylline and Theophylline can cause side effects, although not everyone experiences them.
Common side effects may include:
Seek prompt medical attention for repeated or severe vomiting, a rapid or irregular heartbeat, seizures, severe dizziness, or other symptoms that may indicate significant theophylline toxicity.
This is not a complete list of side effects or warnings. Please refer to the product packaging and patient information leaflet supplied with your medicine for complete information and speak with your doctor or pharmacist if you have concerns.
Storage
Store Etofylline and Theophylline according to the instructions shown on the original product packaging.
Keep the medicine in its original packaging.
Protect it from conditions that may affect the tablets, according to the product instructions.
Keep out of reach of children.
Do not use after the expiry date shown on the packaging.