Short Description
Wegovy 0.25mg is an injectable form of semaglutide, a GLP-1 receptor agonist. It is generally used, alongside a reduced-calorie diet and increased physical activity, to support weight management in adults with obesity or excess weight who also have weight-related health conditions. The 0.25mg strength is the standard starting dose used when beginning treatment.
What Is Wegovy 0.25mg?
Wegovy 0.25mg contains semaglutide, a once-weekly injectable medicine belonging to a class known as GLP-1 receptor agonists. It works by acting on gut hormone pathways involved in appetite and blood sugar regulation.
This strength is used as the initial dose when starting Wegovy treatment. It is not intended to produce the full weight-management effect on its own; instead, it allows the body to adjust to the medicine before the dose is gradually increased over subsequent weeks under medical supervision. Wegovy is not a form of insulin and is not the same product as Ozempic, which is approved for a different indication.
Uses
Wegovy 0.25mg may be prescribed to:
Begin treatment as part of a dose-escalation schedule supporting weight management, alongside a reduced-calorie diet and increased physical activity, in adults with obesity, or with excess weight (overweight) along with at least one weight-related health condition
The appropriate treatment and dose should be determined by a healthcare professional based on individual health needs.
How Does Wegovy Work?
Wegovy works by mimicking a natural gut hormone called GLP-1. By activating GLP-1 receptors, it helps regulate appetite and food intake signals in the brain, slows down how quickly the stomach empties, and supports more stable blood sugar levels.
At this starting strength, the dose is generally too low to produce a significant weight-management effect on its own. Its purpose is to allow the digestive system to adjust to the medicine, which can help reduce the likelihood of gastrointestinal side effects as the dose is increased in later weeks.
How to Take Wegovy
Take Wegovy exactly as prescribed by your healthcare professional.
Usually injected once weekly, on the same day each week, for the first 4 weeks of treatment
Can generally be taken with or without food
May be taken at any time of day
Injected subcutaneously (under the skin) into the abdomen, thigh, or upper arm, rotating the injection site with each dose
Do not continue at this starting dose beyond the prescribed period, and do not stop or change your dose without speaking to your healthcare professional first
Missed dose: If a dose is missed, it should generally be administered as soon as possible within 5 days of the missed dose. If more than 5 days have passed, the missed dose should be skipped and the next dose taken on the regularly scheduled day. Speak with your pharmacist or doctor if you are unsure what to do after a missed dose.
Important Safety Information
Before starting Wegovy, tell your doctor or pharmacist about your full medical history and all medicines, supplements, and herbal products you use.
Caution may be needed in people with:
A personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
A history of pancreatitis
Diabetic retinopathy
Gallbladder disease
Kidney problems, particularly if experiencing dehydration
Depression or suicidal thoughts, past or present
Known hypersensitivity to semaglutide or any ingredient in Wegovy
Wegovy may interact with other medicines, particularly:
Insulin or sulfonylureas (may increase the risk of low blood sugar in people with type 2 diabetes)
Other medicines taken by mouth, as Wegovy can slow stomach emptying and affect how they are absorbed
Always check for possible interactions with a doctor or pharmacist before starting or combining medicines.
Pregnancy & Breastfeeding
Wegovy is generally not recommended during pregnancy, as animal studies suggest a potential risk to the developing baby and there is limited data in humans; treatment is typically stopped in advance of a planned pregnancy. It is also generally not recommended while breastfeeding due to limited safety data. Anyone who is pregnant, planning a pregnancy, or breastfeeding should speak with their doctor or pharmacist before using this medicine, as recommendations may vary depending on individual circumstances and local guidance.
Side Effects
Like all medicines, Wegovy can cause side effects, although not everyone experiences them.
Common side effects may include:
Nausea
Diarrhoea
Vomiting
Constipation
Abdominal pain
Headache
Fatigue
Seek prompt medical attention for symptoms such as severe or persistent abdominal pain (which may indicate pancreatitis), signs of a serious allergic reaction (such as swelling of the face, lips, or throat, or difficulty breathing), vision changes, or new or worsening mood changes.
This is not a complete list of side effects or warnings. Please refer to the product packaging and patient information leaflet supplied with your medicine for complete information and speak with your doctor or pharmacist if you have concerns.
Storage
Store Wegovy according to the instructions shown on the original product packaging.
Keep in the original packaging to protect from light
Keep out of reach and sight of children
Do not use after the expiry date shown on the packaging
