Short Description
Amlodipine 5 mg + Perindopril erbumine 4 mg combines a calcium channel blocker and an ACE inhibitor to help manage high blood pressure (hypertension). These medicines work in different ways to relax blood vessels and reduce the resistance against which the heart pumps.
What Is Empagliflozin 10mg Tablet?
Empagliflozin 10mg Tablet contains empagliflozin, an SGLT2 inhibitor that acts on the kidneys to reduce the amount of glucose reabsorbed into the bloodstream.
It may be prescribed to improve blood glucose control in adults with type 2 diabetes. Depending on local approvals and the patient's condition, it may also be used to reduce the risk of certain complications associated with heart failure and chronic kidney disease.
Uses
Empagliflozin 10mg Tablet may be prescribed to:
Improve blood glucose control in people with type 2 diabetes, alongside diet, physical activity, and other treatment when needed.
Reduce the risk of cardiovascular death or hospitalisation in certain people with heart failure.
Help reduce the risk of kidney disease progression and related complications in eligible patients with chronic kidney disease.
Reduce cardiovascular risk in certain people with type 2 diabetes and established cardiovascular disease, where approved.
The appropriate treatment and dose should be determined by a healthcare professional based on the patient's medical history, kidney function, and the condition being treated.
How Does Empagliflozin Work?
Empagliflozin blocks a kidney protein called sodium-glucose cotransporter-2 (SGLT2). This reduces glucose reabsorption and allows more sugar to leave the body through urine, helping lower blood glucose levels.
It also affects how the body handles sodium and fluid, which contributes to its benefits in certain heart and kidney conditions. Its effects on blood glucose can begin within hours, while the benefits for heart failure or kidney disease may develop over a longer period.
How to Take Empagliflozin 10mg Tablet
Take Empagliflozin 10mg Tablet exactly as prescribed by your healthcare professional.
It is generally taken once daily, according to the prescribed treatment plan.
It can usually be taken with or without food.
Try to take it at the same time each day.
Swallow the tablet whole with water.
Maintain adequate fluid intake as advised by your healthcare professional.
Do not stop treatment or change the dose without medical advice. Your doctor may recommend temporarily stopping it during certain illnesses, before surgery, or when prolonged fasting is required.
If you miss a dose, follow the instructions in the patient information leaflet or ask your pharmacist. Do not take a double dose to make up for a missed dose.
Important Safety Information
Tell your doctor or pharmacist about your medical history and all medicines, supplements, and herbal products you use before starting empagliflozin.
Use this medicine with particular caution if you have:
Kidney problems: Kidney function should be assessed before and during treatment as appropriate.
Low blood pressure or dehydration: Empagliflozin can increase fluid loss and may cause dizziness or low blood pressure.
A history of diabetic ketoacidosis: This is a serious condition that can occur even when blood glucose is not markedly elevated.
Recurrent urinary or genital infections: The medicine can increase the risk of certain infections.
Planned surgery, prolonged fasting, or severe illness: These situations may increase the risk of ketoacidosis and may require temporary interruption of treatment under medical guidance.
Important interactions include:
Insulin and sulfonylureas: These medicines may increase the risk of low blood sugar when used with empagliflozin.
Diuretics (water tablets): These may increase fluid loss and the risk of dehydration or low blood pressure.
Other medicines affecting kidney function, blood pressure, or fluid balance: Your healthcare professional may need to monitor your treatment more closely.
Seek urgent medical attention if you develop symptoms such as nausea, vomiting, abdominal pain, unusual tiredness, or difficulty breathing, which may indicate diabetic ketoacidosis. Check possible interactions and precautions with your doctor or pharmacist.
Pregnancy & Breastfeeding
Empagliflozin is generally not recommended during pregnancy because of limited human safety data and concerns about potential effects on fetal kidney development, particularly during the second and third trimesters. If you are pregnant or planning a pregnancy, your doctor should review your treatment and may recommend an alternative.
Empagliflozin is also generally not recommended while breastfeeding because its effects on a nursing infant, particularly kidney development, are not sufficiently established. Speak with your doctor or pharmacist before using this medicine during pregnancy, when planning a pregnancy, or while breastfeeding.
Side Effects
Like all medicines, Empagliflozin can cause side effects, although not everyone experiences them.
Common or recognised side effects include:
Genital yeast infections, including thrush
Increased urination
Urinary tract infections
Itching or skin rash
Dehydration, dizziness, or low blood pressure
Low blood sugar, particularly when taken with insulin or sulfonylureas
Seek prompt medical attention for signs of diabetic ketoacidosis, severe dehydration, a serious urinary or genital infection, or a severe allergic reaction. Symptoms may include vomiting, abdominal pain, rapid or difficult breathing, fever with significant urinary symptoms, severe genital pain or swelling, or swelling of the face or throat.
This is not a complete list of side effects or warnings. Please refer to the product packaging and patient information leaflet supplied with your medicine for complete information and speak with your doctor or pharmacist if you have concerns.
Storage
Store Empagliflozin 10mg Tablet according to the instructions shown on the original product packaging.
Keep the tablets in their original packaging until needed.
Protect them from excessive heat and moisture.
Keep the medicine out of reach of children.
Do not use the tablets after the expiry date.
Follow any additional storage instructions provided by the manufacturer.
