Short Description
Dapagliflozin 10mg is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes, certain types of chronic heart failure, and chronic kidney disease. It works by helping the kidneys remove excess glucose and sodium from the body through urine, supporting blood sugar control and, in some patients, broader cardiovascular and kidney protection.
What Is Dapagliflozin 10mg?
Dapagliflozin 10mg contains dapagliflozin as its active ingredient, a medicine belonging to the SGLT2 inhibitor class. Unlike many other diabetes medicines, it acts on the kidneys rather than directly on insulin production or sensitivity.
At the 10mg strength, dapagliflozin is used both for additional blood sugar control in type 2 diabetes and, separately, for certain heart failure and chronic kidney disease indications, in people with or without diabetes. Its role within an individual's overall treatment plan should be determined by a healthcare professional based on the specific condition being treated.
Uses
Dapagliflozin 10mg may be prescribed to:
Improve blood sugar control in adults with type 2 diabetes
Treat certain types of chronic heart failure
Treat certain patients with chronic kidney disease
The appropriate treatment should be determined by a healthcare professional based on the individual's condition.
How Does Dapagliflozin Work?
Dapagliflozin blocks a protein in the kidneys called SGLT2, which normally reabsorbs glucose and sodium back into the bloodstream after the blood is filtered. By inhibiting this protein, dapagliflozin allows more glucose to be removed from the body through urine, which helps lower blood sugar levels, and also affects how the kidneys handle sodium and fluid.
This mechanism works independently of insulin. In heart failure and chronic kidney disease, effects on fluid balance and kidney filtration pressure are thought to contribute to the benefits seen, separate from any blood-sugar-lowering effect.
Improvements in blood sugar generally begin within the first days of treatment, while benefits related to heart failure or kidney function tend to develop over a longer period and should be assessed by a healthcare professional.
How to Take Dapagliflozin
Take Dapagliflozin exactly as prescribed by your healthcare professional.
Usually taken once daily
Can generally be taken with or without food
Try to take it at the same time each day to maintain consistent effects
Swallow the tablet whole; do not crush or chew unless advised otherwise
Do not stop or change your treatment without speaking to your doctor or pharmacist first, even if you feel well or your test results improve
Missed dose: If a dose is missed, it should generally be taken as soon as remembered unless it is almost time for the next dose, in which case the missed dose should be skipped. Do not take a double dose to make up for a missed one. If unsure, check with your pharmacist or doctor.
Important Safety Information
Before starting Dapagliflozin, tell your doctor or pharmacist about your full medical history and all medicines, supplements, and herbal products you currently use.
Caution may be needed in people with:
Type 1 diabetes or a history of diabetic ketoacidosis
Reduced kidney function
A history of urinary tract infections or genital infections
Low blood pressure or a tendency toward dehydration
Liver problems
A low-sodium diet or planned surgery
Dapagliflozin may interact with certain other medicines, including:
Insulin and other medicines that lower blood sugar (which may increase the risk of low blood sugar when combined)
Diuretics ("water tablets"), which may increase the risk of dehydration and low blood pressure
This is not a complete list of precautions or interactions. Always check for possible interactions with your doctor or pharmacist before starting this medicine.
Pregnancy & Breastfeeding
Dapagliflozin is generally not recommended during pregnancy, particularly in the second and third trimesters, as it may affect fetal kidney development. It is also generally not recommended while breastfeeding, as it is not known whether it passes into breast milk. Recommendations may vary depending on individual circumstances, so speak with your doctor or pharmacist if you are pregnant, planning a pregnancy, or breastfeeding.
Side Effects
Like all medicines, Dapagliflozin can cause side effects, although not everyone experiences them.
Common side effects may include:
Genital yeast infections
Urinary tract infections
Changes in urination, such as increased frequency or urgency
Nasal or throat symptoms (e.g., stuffy or runny nose)
Dizziness
Seek prompt medical attention if you experience signs of diabetic ketoacidosis (such as nausea, vomiting, abdominal pain, unusual tiredness, or difficulty breathing), symptoms of dehydration or low blood pressure (such as fainting or severe dizziness), or signs of a kidney or severe genital infection (such as fever, pain, or swelling in the genital area).
This is not a complete list of side effects or warnings. Please refer to the product packaging and patient information leaflet supplied with your medicine for complete information and speak with your doctor or pharmacist if you have concerns.
Storage
Store Dapagliflozin according to the instructions shown on the original product packaging.
Keep in the original packaging to protect from moisture
Keep out of reach and sight of children
Do not use after the expiry date shown on the packaging